MURPHY, JAMES M. (Professor) Ph.D. 1978, Bowling Green State University; M.A. 1974, Bowling Green State University; B.A. 1971, Edinboro University of Pennsylvania.   Areas of Specialization: Psychopharmacology, Neurochemistry and Neurobiology of Behavior. Research interests include the neurochemical correlates and determinants of addictive behaviors, behavioral arousal, motivational states, and learning and memory. Current research is concerned with an animal model of alcohol abuse and alcoholism.  Research focus is on hereditary predispositions to excessive alcohol drinking behavior, sensitivity to alcohol, and tolerance to alcohol.

Rodd-Henricks, Z.A., McKinzie, D.L., Shaikh, S.R., Murphy, J.M., McBride, W.J., Lumeng, L., and Li, T.-K. (2000). The alcohol deprivation effect is prolonged in the alcohol preferring (P) female rat following repeated deprivations. Alcoholism: Clinical and Experimental Research 24: 8-16.

McKinzie, D.L., Sajdyk, T.J., McBride, W.J., Murphy, J.M., Lumeng, L., Li, T.-K., and Shekhar, A. (2000).  Acoustic startle and fear-potentiated startle responding in alcohol-preferring (P) and -nonpreferring (NP) lines of rats. Pharmacology Biochemistry and Behavior 65:691-696.

Nowak, K.L., McBride, W.J., Lumeng, L., Li, T.-K., and Murphy, J.M. (2000) Involvement of dopamine D2 autoreceptors in the ventral tegmental area on alcohol and saccharin intake of the alcohol preferring P rat. Alcoholism: Clinical and Experimental Research 24: 476-483.

Nowak, K.L., Ingraham, C.M., McKinzie, D.L., McBride, W.J., Lumeng, L., Li, T.-K., and Murphy, J.M. (2000) An assessment of novelty-seeking behavior in alcohol-preferring and non-preferring rats. Pharmacology Biochemistry and Behavior 66: 113-121.

Rodd-Henricks, Z.A., McKinzie, D.L., Crile, R.S., Murphy, J.M., and McBride, W.J. (2000) Regional heterogeneity for the intracranial self-administration of ethanol within the ventral tegmental area of Wistar rats. Psychopharmacology 149: 217-224

Engleman, E.A., McBride, W.J., Wilber, A.A., Shaikh, S.R., Eha, R.D., Lumeng, L., Li, T.-K., and Murphy, J.M. 2000) Reverse microdialysis of a dopamine uptake inhibitor in the nucleus accumbens of alcohol-preferring rats: Effects on dialysate dopamine levels and ethanol intake. Alcoholism: Clinical and Experimental Research 24: 795-801

Rodd-Henricks, Z.A., McKinzie, D.L., Murphy, J.M., McBride, W.J., Lumeng, L., and Li, T.-K. (2000) The expression of an alcohol deprivation effect in the high-alcohol-drinking replicate rat lines is dependent upon repeated deprivations. Alcoholism: Clinical and Experimental Research 24: 747-753

Rodd-Henricks, Z.A., McKinzie, D.L., Edmundson, V.E., Dagon, C.L., Murphy, J.M., McBride, W.J., Lumeng, L., and Li, T.-K. (2000) Effects of 5-HT3 receptor antagonists on daily alcohol intake under acquisition, maintenance, and relapse conditions in alcohol-preferring (P) rats. Alcohol 21: 73-85
 

James M. Murphy, Ph.D.
Department of Psychology
School of Science
Indiana University Purdue University at Indianapolis
402 North Blackford Street, LD126C
Indianapolis, IN 46202-3275